Modern flow cytometry dates back to the early 1970s when a team at Stanford University, led by Leonard Herzenberg, merged antibodies tagged with fluorescent labels with cell sorting and ...

In a sample prepared with, for instance, a fluorescently labelled antibody, cell-surface markers can be analysed for diagnosis and disease phenotyping — flow cytometry can count cancer-induced ...

ANTIBODY TITRATION is critical to the success of any flow cytometry experiment. This is even more so in microflow cytometric analysis of extracellular vesicles (EVs), where removing excess antibodies ...

After new users become familiar with flow cytometry instrumentation and learn how to set up the instrument and acquire data, the next topic to master is antibody panel design. Optimizing a multicolor ...

The anti-FMC63 scFv monoclonal antibody’s performance was verified in house through flow cytometry (FCM), and it was found to be ideal for the detection of FMC63-derived anti-CD19 CARs in ...

Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...

Novel CD37 antibody-drug conjugate shows promise in targeting the Achilles’ heel of acute myeloid leukemia cells.