G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research. Diabetes results from ...

Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions. Their ...

Ozempic and Wegovy do the same thing as GLP-1 would normally do for you — but to enable them to treat diabetes and obesity, ...

A recent study published in Nature by a research team from the United States and China introduced a new class of engineered G-protein-coupled receptors (GPCRs) called programmable antigen-gated ...

The 2012 Nobel Prize for Chemistry has been awarded to Robert Lefkowitz and Brian Kobilka for groundbreaking discoveries that reveal the inner workings of G-protein-coupled receptors. Professor David ...

A recently published paper in Science China Life Sciences reports an interdisciplinary study utilizing single-cell sequencing ...

Predators and prey in the ocean rely on chemical signals for survival, but this vital sensory mode can also be their Achilles' heel.

Pheno Therapeutics Limited., a biotechnology company focused on the discovery and development of small molecule therapeutics ...