Glutathione (GSH) insufficient promotes the occurrence of ferroptosis (Stockwell et al., 2017 ... cysteine and glycine co-synthesize glutathione (GSH), which is oxidized by glutathione peroxidase 4 ...

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However, the liver's robust antioxidant defenses, including glutathione (GSH) and vitamin E, question the widespread applicability of ferroptosis as a primary mode of cell death in DILI.

The pathogenesis of psoriasis is quite complex and the result of the interplay of genetic, environmental and immune factors. Ferroptosis is an iron-dependent programmed death that is different from ...

From the GO analysis, we screened the upregulated differentially expressed genes and identified key pathways, including mitophagy, autophagy, ferroptosis, apoptosis, nonalcoholic fatty liver disease ...

a Department of Surgery, University of Heidelberg, Heidelberg, Germany, b Department of Immunochemistry, German Cancer Research Center, Heidelberg, Germany Dr B Sido, Department of Surgery, University ...