Nature9 年
Preclinical targeting of human T-cell malignancies using CD4-specific chimeric antigen ...
Here we have designed a CAR, CD4CAR, which redirects the antigen specificity of CD8+ cytotoxic T cells to CD4-expressing cells. CD4CAR T cells derived from human peripheral blood mononuclear cells ...
Nature11 天
CD8-positive T cells articles from across Nature Portfolio
CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...