Based on this, we have developed a new approach to enhance the efficiency of rAAV-mediated gene expression. This approach uses co-infection with a transgene-containing vector and a second vector ...

The Gene Vector Core was awarded the Blue Flame Award ... Infectious titers and other quality control assays may be subject to an additional charge. The core has various expression cassettes and basic ...

This article examines viral and non-viral vectors in gene therapy, highlighting their mechanisms, advantages, and limitations ...

Adenoviral vectors will transduce a wide range of target cells resulting in high-level gene expression. They are non-integrating vectors so expression in dividing cells is progressively lost. First ...

Other groups of rats were used for additional analyses of gene and protein expression; these included rats dosed with AAVlac or the control vector AAVluc (expressing luciferase). These rats were ...

Vaccinia virus (VACV) confers cross-protective immunity against variola virus, the causative agent of smallpox, and has therefore been extensively exploited as a preventive vaccine. Despite the global ...

Vector insertion in the AML cells from this ... Insertion into the VAMP4 gene has had no impact on gene expression or gene regulation nor caused any disruption of nearby genes, bluebird added.

Inhibition of HBV replication by delivering the dual-gene expression vector pHsa-miR16-siRNA in HepG2.2.15 cells.

which accelerates gene therapy vector engineering by generating high-performance out-of-distribution capsid proteins. About Dyno Therapeutics Dyno Therapeutics is building high-performance genetic ...