The primary goal of mouse mutagenesis programmes is to develop a fundamental research infrastructure for mammalian functional genomics and to produce human disease models. Many large-scale ...

“and we hope to combine our data with the Korean Animal Model Archive to help build a national genetic variation dataset.” In 2013, the KMPC joined the International Mouse Phenotyping ...

1.2.3 The mouse as a model prior to the recombinant DNA revolution With the demonstration in the mouse of genetic factors that impact upon cancer, millions upon millions of animals were used to ...

Researchers at Karolinska Institutet have uncovered new insights into the mechanisms underlying autism spectrum disorder (ASD ...

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal ...

That's an important step forward, given that most mouse-model research into dementia focuses ... no single gene causes Alzheimer's—that's not how complex genetics works," Carter explained.

Collaborative research is driving the development of future treatments to ease symptoms of autism and epilepsy. The ...

Genetic changes are a significant cause of infertility, impacting over 15% of the global population. TLE6, a major protein ...

Two new compounds may be able to treat retinitis pigmentosa, a group of inherited eye diseases that cause blindness. The ...