This highlights the importance of genetic background in pharmacological ... when designing experiments and interpreting results in mouse model research[4]. Phenotype: The observable physical ...

1.2.3 The mouse as a model prior to the recombinant DNA revolution With the demonstration in the mouse of genetic factors that impact upon cancer, millions upon millions of animals were used to ...

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends ...

That's an important step forward, given that most mouse-model research into dementia focuses ... no single gene causes Alzheimer's—that's not how complex genetics works," Carter explained.

Intestinal fibrosis, as a late-stage complication of inflammatory bowel disease (IBD), leads to bowel obstruction and requires surgical intervention, significantly lowering the quality of life of ...

Collaborative research is driving the development of future treatments to ease symptoms of autism and epilepsy. The ...

New study reveals that TLE6 protein deficiency causes male infertility in mice. These findings suggest potential genetic ...

Two new compounds may be able to treat retinitis pigmentosa, a group of inherited eye diseases that cause blindness. The ...

Researchers say study represents a resource that could also help to dissect Y-gene functions in other tissues.