People love the taste of sugar beets' primary byproduct: white sugar. Soilborne cyst nematodes—parasitic, microscopic ...

Gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors and were among the first solid tumor types for which such a novel treatment (in this case imatinib) became available. The ...

An approach using engineered small extracellular vesicles from NK cells to DR5 could be a promising strategy for solid tumors ...

Sex cord stromal cells help germ cells grow. Germ cell tumors are rare, so very few young people get germ cell cancer. Out of every 100 children and teens under age 20 who have cancer, only 4 of them ...

However, these treatments display less activity in the absence of alternative therapeutic options. Therefore, it is critical to identify novel actionable alterations in SDH-deficient GIST. Seventeen ...

Combining surgery with chemotherapy significantly improves survival in GIST patients with liver metastases compared to chemotherapy alone. Median CSS and OS for combined treatment exceed 120 months, ...

Treatment with bezuclastinib plus Sutent led to safe and efficacious outcomes versus Sutent treatment alone in gastrointestinal stromal tumors.

Acquisition includes IDRX-42, a highly selective KIT tyrosine kinase inhibitor (TKI) designed to treat gastrointestinal stromal tumours (GIST) IDRX-42 offers potential to address all key KIT ...

has found that treatment targeting the non-tumor, stromal cells in pancreatic cancer with an aim of reverting them to a resting state can improve patient outcome. The study, published in the ...

GIST usually occurs in the GI tract, with 80 percent of cases caused by mutations in the KIT gene. The mutations promote the growth and survival of tumor cells. After first-line treatment ...

FDA Adds Warning For Rare Neurological Disorder GIST typically presents in the GI tract, with 80% of cases driven by mutations in the KIT gene that lead to tumor cells’ growth, proliferation ...