Medscape11d
Drug Insight: Gastrointestinal Stromal Tumors (GIST)--The Solid Tumor Model for Cancer-Specific Treatment
Gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors and were among the first solid tumor types for which such a novel treatment (in this case imatinib) became available. The ...
Cure Today2d
Neoadjuvant TKI Prior to Surgery Has Surgical Benefit in Non-Metastatic GIST
Patients with non-metastatic GIST treated with neoadjuvant TKIs prior to surgery experienced a benefit which led to less ...
ascopubs.org1mon
Targeted Next-Generation Sequencing in Succinate Dehydrogenase–Deficient GI Stromal Tumor Identifies Actionable Alterations in the PI3K/mTOR Pathway
Therefore, it is critical to identify novel actionable alterations in SDH-deficient GIST. Seventeen tumor samples from 14 patients with SDH-deficient GIST underwent NGS. Mutational load was low, ...
Cure Today16d
Bezuclastinib Plus Sutent May Be Safe and Effective in GIST
Treatment with bezuclastinib plus Sutent led to safe and efficacious outcomes versus Sutent treatment alone in gastrointestinal stromal tumors.