The laboratory has identified genetic drivers of malignant progression of glioma. The lab is also focused on understanding how the tumor microenvironment influences the growth of tumor cells. The ...
Researchers have described the development of a novel murine model of glioblastoma established with a patient-derived xenograft (PDX) in humanized mice that harbored an almost complete human immune ...
An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. Cancer development and ...
Leveraging advancements in spatially resolved single-cell profiling, our study enhances understanding of glioma evolution and the complex tumor microenvironment. Through spatially resolved multi-omic ...
As a parent, you may feel a number of emotions when you learn that your child has a pediatric low-grade glioma (pLGG), a type of slow-growing, cancerous brain or spinal tumor that can develop in ...