Findings suggest targeting neuro-immune pathway could lead to strategies for managing diabetes, obesity or some types of ...

A new study has uncovered a critical role for the enzyme Glucose-6-phosphatase 2 (G6PC2) in regulating blood sugar levels.

Israeli and American researchers uncovered the role of a specific enzyme in managing blood sugar levels in a study that opens up new therapeutic possibilities for people with type 2 diabetes. Type 2 ...

New study shows that the gene G6PC2 plays an important role in regulating glucagon, a hormone that raises blood sugar levels.

When we think about the immune system, we usually associate it with fighting infections. However, a study published in Science by the Champalimaud Foundation reveals a surprising new role.

Within islets, beta cells secrete insulin, and alpha cells secrete glucagon. Scientists have identified three additional cell types in islets, including cells that secrete the hormones ...

However, in people with diabetes, the pancreas does not secrete insulin, or the cells are not sensitive to its effects. The ...

Objective—Glucagon-like peptide 1 (GLP-1) exerts beneficial antidiabetic actions via effects on pancreatic β- and α-cells. Previous studies have focused on the improvements in β-cell function ...

Furthermore, GLP-1 also reduces glucagon secretion from pancreatic alpha cells, resulting in a reduction in hepatic glucose output. Metformin is an antihyperglycemic agent which improves glucose ...