Nature2mon
The renaissance of GSK3
Glycogen synthase kinase 3 (GSK3) was initially described as a key enzyme involved in glycogen metabolism, but is now known to regulate a diverse array of cell functions. The study of the ...
Aro Biotherapeutics Doses First Patient in Phase 1b Trial of ABX1100 in Late-Onset Pompe Disease (LOPD)
Aro Biotherapeutics, a clinical-stage biotechnology company working to develop potent and tissue-targeted medicines, today announced the dosing of the first patient in its clinical trial of ABX1100, a ...
BMJ2y
Effect of testosterone and endurance training on glycogen metabolism in skeletal muscle of chronic hyperglycaemic female rats
Tables 2 and 3 show the activities of glycogen synthase and glycogen phosphorylase in EDL and soleus muscles respectively. The lower glycogen content of these muscles in sedentary hyperglycaemic rats ...
University of Delaware4mon
Donna Woulfe
Akt2-/- mice are also resistant to thrombosis in an arterial injury model. In contrast, the Akt substrate, Glycogen synthase kinase (GSK)3beta, is a negative regulator of platelet signaling and ...
Yahoo Finance22d
Actuate Therapeutics Receives EMA Orphan Medicinal Product Designation for Elraglusib for the Treatment of Pancreatic Cancer
difficult-to-treat cancers through the inhibition of glycogen synthase kinase-3 beta (GSK-3β), today announced that the European Medicines Agency (EMA) has granted Orphan Medicinal Product Designation ...