Sequence variations in human immunodeficiency virus (HIV)-1 reverse transcriptase (RT) and protease, the molecular targets of anti-retroviral drug therapy, are prime examples of genes in which ...
Caption: Structure of a HIV capsid (Left) Central slice view of a HIV virus-like particle with pore-forming toxin on the membrane (Middle) Atomic model of a HIV capsid (Right) Density map of HIV ...
and the NucliSens™ HIV-1 QT system by bioMerieux Inc (commonly known as the NASBA assay originally owned by Organon Teknika Co.). The Amplicor Monitor™ is a RT-PCR based testing system ...
NRTIs are converted to their active 5'-triphosphate forms inside cells and compete with dNTPs for HIV RT. In addition, as NRTIs lack a 3'-hydroxyl group, they function as a chain terminator and ...
TAM-containing RT demonstrates enhanced excision activity ... Stereogram for the 3D structure of HIV-1 reverse transcriptase in complex with a DNA template-primer and dTTP. The p66 subunit ...
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