The general principles of how viruses move between target cells and tissues ... engage more than one receptor to enter the cell (for example, HIV-1 (Ref. 1); Table 1). Immunological barriers ...
For HIV, the viral envelope promotes fusion of ... This challenge becomes even more daunting if the target cell is not in mitosis when the virus is trying to access the nucleus.
But Dr Jonathan Stoye, a virus expert at the Francis Crick Institute, in London, said removing HIV from all the cells that might harbour it in the body was "extremely challenging". "Off-target ...
They say the next steps involve optimising the delivery route to target the majority of the HIV reservoir cells. The hope is to devise a strategy to make this system as safe as possible for future ...
Scientists have unveiled insights into how HIV-1, the virus responsible for AIDS, skillfully hijacks cellular machinery for its own survival. By dissecting the molecular interplay between the virus ...
Determinants of HIV cell tropism & chemokine receptor usage ... with generation of strains resistant to antiretrovirals that target viral proteins such as reverse transcriptase.
China aims to keep its HIV prevalence rate below 0.2 percent by 2030, according to a policy document released this week, as high infection rates among men who have sex with men and covert ...