The study analyzed PVs in the HRAS or KRAS gene ... found in mosaic RASopathies overlaps with the spectrum of gene mutations ...

Revolution Medicines Inc. has synthesized macrocyclic compounds acting as GTPase KRAS, NRAS, HRAS and their mutant inhibitors reported to be useful for the treatment of cancer. BioWorld Science Cancer ...

While generally rare, HRAS mutations are principal in bladder and head and neck squamous cell carcinomas (HNSCC). RAS mutations play well-defined parts in the development of divergent cancers.