As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

Neither biliary markers, such as CK19 ... Moreover, the cells act on hepatic stellate cells, a key driver of hepatic fibrosis. This gives such liver-derived progenitor cells anti-inflammatory ...