These mechanisms suggest a tight link with chromatin modification and gene expression. A great deal of effort is being put into identifying drugs that target histone modifications. Hopefully ...
Thus, histone modifications generally represent a more complex and diverse mechanism to affect gene transcription than DNA methylation. In fact, one effect of DNA methylation can be to recruit ...
The following is a summary of “Histone Modifications and DNA Methylation in Psoriasis: A Cellular Perspective,” published in ...
Epigenetic regulation is a key mechanism in the fibrogenic ... Post-translational histone modifications, such as acetylation, ...
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