现有 scRNA-seq 分析算法常采用每 10K 计数（CP10K）归一化方法，该方法虽能消除技术因素影响，但同时也去除了由生物变化引起的转录组大小差异，导致基因表达水平出现不均衡的缩放效应，影响了不同细胞类型间差异表达基因（DEGs）的准确识别。 批量 RNA 测序虽 ...

Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory for Digestive Health, National Clinical Research Center for Digestive Disease, Beijing ...

Gene Ontology (GO) analysis of up-regulated DEGs highlighted their involvement ... of-function VvDELLA1 in L1 dwarf grape mutants, RNA sequencing (RNAseq) profiling was conducted on shoot apices ...