Introduction: Recombinant human fibroblast growth factor 21 (FGF-21) is a potential therapeutic agent for multiple metabolic diseases. However, little is known about the toxicokinetic characteristics ...

We demonstrate here that cell surface expression of HSPG alone is insufficient for AAV infection, and that AAV also requires human fibroblast growth factor receptor 1 (FGFR1) as a co-receptor for ...

The spread of the Aedes aegypti mosquito, which transmits the Zika virus as well as dengue, Rift Valley fever, and ...

Background Fibroblast to myofibroblast transition is believed to contribute to airway remodelling in lung diseases such as asthma and chronic obstructive pulmonary disease. This study examines the ...

Zika virus hijacks the skin of its human host to send out chemical signals that lure more mosquitoes to infect and spread the ...

Therefore, after a review of the available values found in the literature, we performed direct measurements from samples stained by multiplex IHC to study the composition of fibroblasts and ...

This was confirmed by their invasion into human cartilage in the severe combined immunodeficiency mouse fibroblast invasion model in vivo. Conclusions Interaction with activated B cells leads to ...

Therefore, their only source is their attraction to cancer cells, which occurs at a recruitment rate of α TC C, while the crowding limits this recruitment: Thus, the dynamics of the CAFs is purely ...

PURPOSE: To evaluate the role of transforming growth factor beta 1 (TGF-β1) on the induced osteogenic differentiation of human dermal fibroblasts. METHODS: We performed four groups with cultured ...

psu.edu Objectives Rheumatoid Arthritis (RA) is a chronic inflammatory disease of unclear aetiology, which is associated with inflamed human fibroblast-like synoviocytes (HFLS). Epidemiological ...