The hypothalamic–pituitary–thyroid axis plays a crucial role in the pathogenesis, diagnosis, risk stratification, effectiveness of radioiodine therapy, and treatment response evaluation in epithelial ...

This review highlights the key areas of research in the hypothalamic control of appetite. The hypothalamus consists of several nuclei that integrate peripheral signals, such as adiposity and ...

Engaging in moderate exercises like walking, jogging, swimming, or cycling for a minimum of 30 minutes daily increases blood ...

There are projections from the ARC to other hypothalamic nuclei, as well as the cerebral cortex and reward pathways. Multiple neuropeptides have been identified that appear to modulate pathways ...

These genetic disorders result from reduced levels of gonadotropin and sex steroids in the absence of anatomical or functional abnormalities of the hypothalamic–pituitary–gonadal axis.

Setmelanotide, an investigational melanocortin-4 receptor agonist, reduced body mass index (BMI) by a mean 15% at 16 weeks and 26% at 12 months in people with hypothalamic obesity in a phase II ...

Mutations in a gene called OTP cause obesity by controlling the output of another gene already targeted by an anti-obesity drug, a study led by UT Southwestern Medical Center researchers shows. The ...

The following is a summary of “Treatment of Hypothalamic Obesity With GLP-1 Analogs,” published in the November 2024 issue of Endocrinology by Dimitri and Roth. Damage to hypothalamic nuclei or ...