to trigger basophil activation. The fact that in this context the BAT does not discriminate between IgE- and non-IgE-mediated reactions, should not be considered as a shortcoming. Finally ...

A recent study reveals the pivotal role of tristetraprolin (TTP), an RNA-binding protein, in regulating inflammatory responses in basophils, immune cells central to allergic reactions. The research ...

Basophils from each strain were stimulated with antigen combined with IgE, IL-33, or lipopolysaccharide (LPS). We measured gene expression, mRNA stability, and inflammatory protein levels.

with anti-IgE or anti-IgE-receptor I, and fail to upregulate expression of CD63 and/or CD203c. Importantly, as activation of the basophil with N-formyl-methionine-leucine-phenylalanine (fMLP ...

Published research shows that a strong IgG-mediated immune response could be both neutralizing against incoming allergens and inhibitory to the programmed IgE-mediated activation of basophil cells ...

Basophils from each strain were stimulated with antigen combined with IgE, IL-33, or lipopolysaccharide (LPS). We measured gene expression, mRNA stability, and inflammatory protein levels.

IgE is believed to bind to and activate immune cells, such as basophils and mast cells. When IgE binds with any of these cells, it can overstimulate your immune system. Additionally, your ...

Basophils from each strain were stimulated with antigen combined with IgE, IL-33, or lipopolysaccharide (LPS). We measured gene expression, mRNA stability, and inflammatory protein levels.

Researchers investigate the cellular and molecular mechanisms through which stress exacerbates immunoglobulin E cutaneous allergic inflammation.