Interestingly, a substantial number of SLE patients produce IgE autoantibodies, suggesting that basophils may contribute to disease severity through their involvement in Th2-associated immunity[2].

to trigger basophil activation. The fact that in this context the BAT does not discriminate between IgE- and non-IgE-mediated reactions, should not be considered as a shortcoming. Finally ...

Basophils from each strain were stimulated with antigen combined with IgE, IL-33, or lipopolysaccharide (LPS). We measured gene expression, mRNA stability, and inflammatory protein levels.

Following receipt of dupilumab for 24 weeks, desensitization to peanut exposure in most children/adolescents with peanut ...

basophil, and programmed death ligand 2 (PD-L2 +) monocyte/macrophage levels did not differ between the groups. This finding implies that restraint stress leads to exacerbation of IgE-CAI with ...

In conclusion, hypersensitivity reactions to NSAIDs are very common but the majority of these reactions are not IgE mediated. Consequently, in most patients BAT will not be useful to document ...