The advent of immunotherapy based on immune checkpoint inhibitors has improved the treatment of advanced hepatocellular ...
The machine learning system SCORPIO can predict patient outcomes with immune checkpoint inhibitor (ICI) therapy across ...
研究首先在真实世界数据集中对SCORPIO进行了全面测试。模型的开发和初步验证基于来自纪念斯隆-凯特琳癌症中心(MSKCC)的近4000名患者的数据,这些患者涵盖了21种癌症类型,并接受了免疫检查点抑制剂(ICIs)治疗。在测试数据集中,SCORPI ...
近年来,以程序性死亡受体-1(programmed death‑1,PD‑1)抗体、程序性死亡蛋白-配体 1(programmed death ligand‑1,PD‑L1)抗体和细胞毒性 T 淋巴细胞相关抗原-4(cytotoxic T ...
(OTCQB: BIXT) (the “Company”), a clinical stage biotechnology company developing oral and intravenous drugs to treat viral diseases, fibrosis, stroke, dementia, and Alzheimer's disease, announced its ...
The PD-1 receptor, a major immune checkpoint inhibitor whose signaling is the target of multiple blockbuster anticancer drugs, differs functionally between rodents and humans in previously unknown ...
The following is a summary of “Lenvatinib and immune-checkpoint inhibitors in hepatocellular carcinoma: mechanistic insights, ...
Doctors around the world may soon have access to a new tool that could better predict whether individual cancer patients will ...
Cancer immunotherapy drugs called immune checkpoint inhibitors take the brakes off the body’s immune system, allowing it to ...
Researchers at Mount Sinai and Memorial Sloan Kettering believe they’ve made a breakthrough in a new form of cancer treatment ...
Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...