This highlights the multifaceted role of CD83 in immune modulation, where it not only regulates macrophage activity but also influences B cell functions to maintain immune homeostasis. Overall ...

This study unveiled the role of Lrrk2 gene in regulating macrophage polarization and immune response. This finding provides ...

Our results suggest that, in non-responding patients, we should be targeting these macrophages to reprogram the tumor immune environment. "We hope our research will enable clinicians to make ...

Pro-inflammatory macrophages drive inflammation by releasing ... the extracellular matrix of tissues like cartilage, in this ...

These cells deal with microbes and repair tissue damage. Two main sub-types of immune cells are T cells and macrophages. T cells are designed to recognise the molecular signatures of particular ...

falciparum expresses different versions of it and escapes immune recognition. 3) Inside macrophages, Mycobacterium tuberculosis dodges intracellular degradation by secreting virulence factors. Two ...

Aligning therapies with the biologic clock may improve efficacy, as macrophage activity peaks early in the morning, worsening inflammatory disease symptoms.

Our livers contain many different types of immune cells. New research by the team of Prof. Charlotte Scott (VIB-UGent Center for Inflammation Research) and colleagues now reveals that a specific ...

Artax's first-in-class oral small molecules aim to deliver immune system modulation without immunosuppression, potentially unlocking new treatment options as both monotherapy and in combination ...