In a pair of recent papers, scientists in the lab of molecular biologist John Petrini, Ph.D., showed that innate immune signaling plays a key role in maintaining genome stability during DNA ...

Contrary to prior data, this study shows that neither eosinophils nor STAT6-mediated IL-4/IL-13 signaling contribute ...

The study of plant host-defense systems has also yielded great insight into the various components required for innate immune signaling. For example, analysis of NBS-LRR proteins has demonstrated ...

our immune system is important for wound healing and our immune system also restricts bacterial pathogens.” Ledvina and Whiteley highlight four such types of signaling pathways of the innate immune ...

The RIG-I activation is tightly regulated via various posttranslational modifications for the prevention of aberrant innate immune signaling. By contrast, viruses have evolved mechanisms of evasion, ...

The Alexander Gitlin Lab studies how inflammatory cell signaling controls the nature and magnitude of inflammation under physiological and disease conditions. Innate immune cells are tasked with ...

Professor Meghan Morrissey earns an innovation award to program immune cells to attack cancer tumors. #immunotherapy ...

The common and important infectious viruses in pigs and poultry mainly include DNA and RNA viruses, which pose significant threats to both animal and human ...

This study unveiled the role of Lrrk2 gene in regulating macrophage polarization and immune response. This finding provides ...