The protein IGFBP7, which is secreted from the liver and has been studied in relation to heart failure and kidney damage, turns out to affect insulin secretion in type 2 diabetes.

Figure 1: The signalling pathway by which insulin inhibits GSK3 and contributes to the stimulation of glycogen and protein synthesis. Figure 4: The molecular mechanism by which phosphorylation ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team.