Both Inceptor and the insulin receptor are located on the surface of ... Inceptor binds to and directs insulin towards lysosomal degradation in β cells, Nature Metabolism (2024).

Heterozygous or complete deletion of the insulin receptor in several tissues, including liver, skeletal muscle, neurons and pancreatic β-cells, leads to varying degrees of insulin resistance or ...

Type 1 diabetes is an autoimmune disorder in which the body's immune cells attack the β-cells ... and after insulin ...