Crystallized alternative DNA structure sheds light on insulin and diabetes
The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team.
Nature4y
G-Protein-Coupled Receptors, Pancreatic Islets, and Diabetes
G-protein coupled receptors regulate hormone secretions in ... levels that stems from the decreased secretion and/or action of insulin. Two major forms of diabetes exist, type 1 and type 2.
BioWorld4d
PTP1B allosteric inhibitor enhances glucose uptake in insulin resistance models
Tyrosine-protein phosphatase non-receptor type 1 (PTP1B) acts as a negative regulator of the insulin signaling pathway by dephosphorylating both the insulin receptor (IR) and the insulin receptor ...