G-protein coupled receptors regulate hormone secretions in ... levels that stems from the decreased secretion and/or action of insulin. Two major forms of diabetes exist, type 1 and type 2.

The Discovery of New Members of the TNF Receptor and Ligand Families and Their Relationship to Osteoclasts and Bone Metabolism Binding of RANKL to RANK initiates a signaling cascade, which ...

The ERBB receptors are a group of receptor tyrosine kinases (RTKs) involved in key cellular functions including cell growth and survival. What are the activation mechanisms particular to ERBBs?

The ability to alter protein binding can create tailored therapeutics with reduced side effects, sensitive diagnostic tools, ...

Epidermal growth factor receptor (EGFR) is a major driver of cancer dissemination and target for anti-cancer therapies but ...