In addition to impaired insulin secretion, type 2 diabetic patients ... who identified insulin as the anti-diabetic factor produced by the pancreas. This discovery changed the once fatal diagnosis ...

For several years, Lena Eliasson's research group has explored mechanisms that regulate insulin secretion from beta cells situated in the islets of Langerhans within the pancreas. Together with ...

Researchers from Lund University, in collaboration with Newcastle University, have uncovered a potential breakthrough in ...

Glucagon-like peptide 1 (GLP-1) could be a key factor driving the development of insulin-producing cells, according to in vitro data published in the journal Pancreas. The use of islet-cell ...

Researchers from Lund University and Newcastle University have found that the protein IGFBP7 can impair the function of beta ...

forces the pancreas to compensate through increased insulin production and secretion. The persistent inability of cells to respond to this increased secretion triggers a positive feedback loop ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion ... defect in pancreas duodenum homeobox ...

New study shows that the gene G6PC2 plays an important role in regulating glucagon, a hormone that raises blood sugar levels.

Findings suggest targeting neuro-immune pathway could lead to strategies for managing diabetes, obesity or some types of ...