Membrane proteins are proteins found in cell membranes, either at the surface or on intracellular organelles. Integral membrane proteins such as receptors and ion channels span the membrane.
However, yeast two-hybrid assays cannot be used to analyze several important protein classes, such as integral membrane proteins or transcription factors. Here we demonstrate the ability of the ...
Over the years, chemical biology methods have made an important contribution to the study of integral membrane proteins. A key modern approach is genetic code expansion (GCE), which makes it ...