Figure 1: Cell-binding assays with a defined α v integrin phage ligand and phage-cell–binding optimization with BRASIL. To test the selection method, we compared 21 phage clones randomly chosen ...

Integrin adhesion molecules are proteins that help inflammatory cells bind to gut tissues. Integrin receptor antagonists ...

Dr. Rainero and her team will study how blocking a2b1 integrin affects breast cancer growth and spread. These studies will be conducted using lab-grown cells, patient samples, and animal models ...

A remarkable development in breast cancer research has revealed a fundamental mechanism behind driving cancer invasion and ...

Janssen opted not to continue with the first two integrin targets at the end of 2021, due to "a lack of target validation in the specific disease of Janssen's interest," and has now dropped the ...