Antibody Therapeutics Inc. has disclosed integrin receptor antagonists reported to be useful for the treatment of pulmonary fibrosis, renal fibrosis and hepatic fibrosis.

VLA-4 antagonists are a class of drugs that target the very late antigen-4 (VLA-4) integrin, which plays a crucial role in the adhesion and migration of immune cells. This mechanism is ...

Biologics work by targeting proteins that cause inflammation in ulcerative colitis. As a result, certain biologics help ...

Lilly has also submitted marketing applications for Mirikizumab-mrkz in Crohn’s disease around the globe, including in the European Union and Japan. Additional global regulatory submissions are ...

Adhesion receptors act as molecular fingertips that ... Functions of the cytoplasmic domain of the beta PS integrin subunit during Drosophila development. Development (Cambridge, England) 120 ...

ORLANDO -- Vedolizumab (Entyvio) and infliximab (Remicade) led to mostly similar 1-year outcomes in patients with ulcerative colitis previously untreated with a biologic, but the integrin receptor ...