The authors suggest that inhibition of IFN-γ signaling could provide a novel approach for the concomitant prevention of inflammation and bone loss in common osteoporotic conditions, including ...

Interferon gamma (IFN-γ) is a cytokine that induces ... These interleukins’ stimulatory effects also result from intracellular signaling of transcription factors such as AP-1, JAK/STAT, and ...

The Katherine King lab members are involved in the study of the role of interferon-gamma in hematopoietic stem cell regulation. Dr. King discusses the impact of receiving an AAMDSIF research grant on ...

Regulatory T cells typically inhibit other immune cells, including those that produce interferon gamma. Knocking out calcium signaling in regulatory T cells unleashed the cells that produce ...

Moreover, we determined a significant upregulation of interferon-gamma signaling in infected BCECs. The latter was also detected in the neurovascular unit (NVU) in post mortem COVID-19 brain by ...

Regulatory T cells typically inhibit other immune cells, including those that produce interferon gamma. Knocking out calcium signaling in regulatory T cells unleashed the cells that produce ...

IFI16 facilitates the inflammatory endothelial pathophenotypes observed among individuals with PAH, according to new research ...

More information: Natsuko Otaki et al, Activation of ILC2s through constitutive IFNγ signaling reduction leads to spontaneous ...