To reduce iron levels in HSCs, the team injected old mice with the iron chelator deferoxamine daily for 14 days. Compared with controls, aged HSCs exposed to iron chelation produced significantly ...

Thalassemia is a congenital blood disorder requiring chronic blood transfusions and daily iron chelation therapy ... transfused and 92% receiving chelation (26% deferoxamine (DFO; a slow ...

José Manuel Fernández-Real, Abel López-Bermejo, and Wifredo Ricart Deferoxamine administration restored motor and sensory nerve conduction velocity and improved nerve blood flow in experimental ...

Researchers recently examined how different iron chelation medications—deferoxamine, deferiprone, and deferasirox—impacted iron stores and long-term health in patients with transfusion ...