1 Furthermore, when researchers subjected them to additional iron restriction by using iron chelators, these cells activated a molecular response that is linked to their regenerative capacity. A ...
To reduce iron levels in HSCs, the team injected old mice with the iron chelator deferoxamine daily for 14 days. Compared with controls, aged HSCs exposed to iron chelation produced significantly ...
coli) and Gram-positive (Staphylococcus aureus) bacteria. Blocking the production of hydroxyl radicals by treatment with an iron chelator, or quenching hydroxyl radicals with thiourea, increased ...