Now, researchers have identified a mechanism by which viral infection can lead to cachexia. In mice infected by a particular virus, killer T cells trigger the wasting of fat tissue and body weight, ...
The body’s defense system against infection also fights tumors, generating tumor resident stem-like T cells and killer T cells that express inhibitory receptors such as PD-1. When PD-1 binds to PD-L1 ...
However, while CAR-T therapies provide a potent treatment ... So instead, Rezvani decided to add the CAR gene to natural killer (NK) cells. “These cells are part of the innate immune system ...
Creating cancer therapies based around natural killer cells could offer similar levels of efficacy to CAR-T therapies, but at around one hundredth of the cost. Researchers at MD Anderson Cancer ...
A sugar produced by soil bacteria may be able to stop the loss of skin pigment caused by vitiligo.  | A sugar produced by ...
Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans. Nature Microbiology , 2025; DOI: 10.1038/s41564-024-01903-7 Cite This Page : ...
A study shares new insights into how two of the most common types of chimeric antigen receptor (CAR) T cells kill cancer. Investigators examined how molecular dynamics at the immune synapse ...
An investigational induced pluripotent stem cell-derived CAR natural killer cell therapy was well ... who had received previous autologous CAR T-cell therapy, an area of continued unmet need ...
Moreover, patients who had undergone prior CD19-directed CAR T-cell therapy had a complete ... [induced pluripotent stem cell]-derived CAR [natural killer] cells are a highly promising approach ...