The malfunctioning mitochondria seem to poison the immune cells, explains Yosuke Togashi, a pulmonary physician and ...

In 2010, a milestone was achieved when the first patient with cancer was treated with CAR-T-cell therapy ... to add the CAR gene to natural killer (NK) cells. “These cells are part of the ...

Researchers have revolutionized cancer immunotherapy by developing a way to grow T cells in the lab that live longer and ...

Creating cancer therapies based around natural killer cells could offer similar levels of efficacy to CAR-T therapies, but at around one hundredth of the cost. Researchers at MD Anderson Cancer ...

Scientists from the University of Pennsylvania have developed an innovative cancer treatment using small extracellular ...

“Our findings actually show how our body’s immune system recognises and attacks these cancer cells. “Killer cells are an ...

where fragments of cancer-associated proteins are designed to boost patients' killer T cells. Dr. Schietinger's team is ...

This enabled fast CAR T cell recovery and a mastery of "serial killing" of cancer cells. In contrast, researchers found that 4-1BB.ζ-CAR molecules linger in the lipid rafts and immune synapse.

Ardolino had encountered trogocytosis in prior work, so he set out to explore whether the process could explain how natural killer cells ended up with PD-1 on their membranes. The study authors used a ...

In mice infected by a particular virus, killer T cells trigger the wasting of fat tissue and body weight, although how they do so is still unclear. The findings were published on Monday (May 20) in ...

T-cell therapies that modify or directly use T-cells to attack cancer. 1 These approaches have benefited certain patients, but cancer is clever, and it can evade and suppress therapies like ...

It was conventionally thought that TVEC worked by activating T cells -- a type of white blood cell -- causing them to attack the cancer cells and shrink the melanoma. However, the team found that ...