This resulted in a human phosphorylation network (HPN) that consists of 7,143 site-specific kinase–substrate interactions between 1,759 substrates and 68 kinases, with predictions for 4,488 ...

Disruption in these kinase-substrate interactions is often ... By focusing on system contexts, such as the network of ...

Following protein concentration determination (by BCA assay), 5-10 μg of protein for the PTK chip (~1 μg for the STK) will be loaded per well of the PamChip along with standard kinase buffer (Supplied ...

What regulates protein kinase activity during cell division ... They sometimes collaborate with each other, making the regulatory network much more complex but also more accurate.

With over 15 years of experience in kinase drug discovery, DiscoverX offers the largest collection of nearly 500 biochemical and cell-based kinase assays. KINOMEscan® technology, our novel kinase ...