Figure 1: Kinase targets in clinical trials and the currently targeted kinome. To evaluate the diversity of kinase targets studied in preclinical and early kinase drug discovery projects ...

To start to delineate the complex network of pathways involving kinases, researchers want to match every kinase in a cell, representing the so-called kinome, to specific phosphorylation sites on ...

In the PamStation®12 system, active kinases within a cellular/tissue lysate will phosphorylate specific peptide substrates within the microarray which survey the particular kinome (tyrosine or ...