Because of these effects, it has been considered a plausible mechanism in the pathway leading from obesity to Alzheimer's disease. It is supported by findings tying higher leptin levels to lower ...

Reiko Hanada; Hitoshi Teranishi; James Todd Pearson; Mamoru Kurokawa; Hiroshi Hosoda; Nobuhiro Fukushima; Yoshihiko Fukue; Ryota Serino; Hiroaki Fujihara; Yoichi Ueta ...

The Nmu gene was targeted for deletion by standard techniques (Supplementary Fig. 1 online). Nmu-/-mice were generated on a BL6/129 mixed background and backcrossed four times into C57BL/6J mice.