a research group developed a highly sensitive proteomics method called peptide-centric local stability assay (PELSA), which enables the simultaneous identification of ligand-binding proteins and ...

The ability to alter proteins to refine control over binding affinity and specificity can create tailored therapeutics with ...

We have used the ligand binding domain of the recombinant human estrogen receptor (hER) to develop a nonisotopic assay for detection of estrogenic compounds. The assay is based on competition of ...

Researchers led by Truong Son Hy, PhD, from the University of Alabama at Birmingham, offer a simplified method they call ProteinReDiff that uses artificial intelligence to speed the redesign of ligand ...

This RT-PCR machine is utilized to perform Thermal Shift Assays, not only as a hit-validation tool to evaluate ligand – protein binding, but also a tool for fragment based drug screen. It accommodates ...

To this end, it is proposed that we should adapt the nanomaterial to the addressed exposure scenario, using ligand-free nanoparticle ... from 'live–dead' assays to the assessment of cell ...

In this webinar we will demonstrate a method to perform 3D tumor invasion assays and mechanism of action determinations. Tumor invasion tracking was performed via digital microscopy and cellular ...

Researchers now offer a simplified method they call ProteinReDiff that uses artificial intelligence to speed the redesign of ligand-binding proteins. In biology, the binding of cellular proteins ...