Which ligand binds which receptor and what partner a receptor ... A quantitative protein interaction network for the ErbB receptors using protein microarrays. Nature 439, 168–174 (2006) doi ...

The ability to alter protein binding can create tailored therapeutics with reduced side effects, sensitive diagnostic tools, ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which ... details of dROS1 interaction with BOSS.

EPFL researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel ...

Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions. Their environments-water, lipid membranes, or other condensed phases-are critical to their ...

Epidermal growth factor receptor (EGFR) is a major driver of cancer dissemination and target for anti-cancer therapies but ...