Therefore, the authors suggest that the lipid metabolism pathways might be coordinately deregulated in cancer and other inflammatory and metabolic diseases, the pathogeneses of which may indeed ...
The authors present an introduction to the basics of lipid metabolism including an overview of the structure and function of lipoproteins and a description of the pathways of lipid metabolism.
The endogenous pathway involves the liver synthesizing lipoproteins. TG and cholesterol ester are generated by the liver and packaged into VLDL particles and then released into the circulation.
Insulin-like growth factors (IGFs) released by regenerating limbs and hepatic insulin signaling pathways are key to help adapting lipid metabolism to meet the needs of cell proliferation.
how they store lipids to buffer fluctuation in their availability, and how these processes function in membrane biology and cell physiology, and how dysfunction of these pathways leads to diseases, ...
pathway, which has been linked to cancer progression. The study also included spatial transcriptomics to map the gene expression of lipid metabolism-related enzymes in colorectal cancer tissues.
This is a useful study that adds new data to how different DAG pools influence cellular signaling, and dissects how the enzyme Dip2 modulates the minor lipid signaling DAG pool, which is distinct from ...