Researchers at the University of Kentucky Sanders-Brown Center on Aging are working to develop a pre-symptomatic disease diagnostic tool for Alzheimer's disease. "While the need for better ...

Long-read, single-molecule DNA sequencing is a foundational method in genomics research, with applications including identifying complex structural variants and analyzing whole chromosomes. However, ...

Genes can produce more than one messenger RNA (mRNA ... so to better capture these, we also used long-read sequencing that reads between 5,000 and 30,000 base pairs at a time and does not ...

Since then, Wobble Genomics, Kuo’s spin-off from the University of Edinburgh, UK, has grown from 2 to 16 employees, and in ...

We integrated high-throughput single-cell 3’-RNA-sequencing with targeted Iso-Seq long-read RNA sequencing on the PacBio Sequel II platform to overlay single-cell genotype with cell-type and gene ...

Here I will present how active promoters can be identified using RNA-Seq data, enabling the analysis of promoter activity in more than 18,000 samples. In order to study novel promoters, we generated ...

PacBio (PACB) announced a significant publication from Radboud University Medical Center and its research partners in the American Journal of ...

MENLO PARK, Calif., Jan. 14, 2025 (GLOBE NEWSWIRE) -- PacBio (NASDAQ: PACB), a leading provider of highly accurate long-read sequencing solutions, announced a significant publication from Radboud ...

Principle of Nanopore Sequencing: DNA/RNA is passed through protein nanopores embedded in ... allowing for the determination of the DNA sequence. PacBio's long read lengths and high consensus accuracy ...