The search for answers to Alzheimer's disease and other neurodegenerative disorders remains one of the most pressing goals in ...

Cutting-edge fluorescent cholesterol probes now enable scientists to visualize cholesterol movement and distribution in live ...

in particular the mechanisms and physiology of neutral lipid synthesis and storage in lipid droplets. More broadly the lab studies the mechanisms how cells regulate the abundance of lipids, how they ...

Cancer cells gobble up lipids. Prostate cells are stained with Oil-Red O to detect lipid droplets. Our work shows that redistribution of lipids from prostate cancer microenvironment triggers ...

Additionally, some variants of the CND probes are pH-sensitive, allowing researchers to track cholesterol movement in organelles with varying acidity, such as lysosomes and lipid droplets.

Researchers believe the key to understanding neurodegenerative diseases may lie in understanding how cholesterol and other ...