gut.bmj13d
Induction of macrophage efferocytosis in pancreatic cancer via PI3Kγ inhibition and radiotherapy promotes tumour control
Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...
Medscape20d
Detection of Macrophages via Paramagnetic Vesicles Incorporating Oxidatively Tailored Cholesterol Ester: An Approach for Atherosclerosis Imaging
Immunohistochemical localization of oxPL contrast agent within atherosclerotic plaque confirmed selective accumulation in macrophages. Phagocytosis of oxPL in human macrophages involves α v β 3 ...
Nature4y
Carisma drives CAR-M engineered macrophage cancer therapy forward
activating nearby antigen presenting cells (APCs), notably dendritic cells (DCs), and repolarizing tumor-associated macrophages (TAMs) toward an M1 phenotype. In addition to direct phagocytosis of ...