Following release from hepatocytes, each merozoite infects an erythrocyte, thus triggering the bloodstream stage of infection and the pathology that is associated with malaria. Earlier research ...

Cerebral malaria (CM) is a complex of syndromes relating to the presence of Plasmodium falciparum-infected erythrocytes sequestering in the brain microvasculature. The mechanisms of pathology are ...

Such drugs will prevent pathology and interrupt transmission, and could therefore have an important role in the control of malaria and its eventual eradication. Given the increased commitment to ...

[150] Cerebral malaria (CM) is a complex of syndromes ... sequestering in the brain microvasculature. The mechanisms of pathology are not fully known but are thought to be related to the ability ...

"The way in which PfEMP1 functions and how it is neutralized by human antibodies are increasingly being uncovered on a structural level and are essential for understanding malaria pathology and ...

A decade and a half later, he was back on campus—this time with malaria as his designated target. The disease persists as one of the developing world’s deadliest, in part because of the difficulty of ...

The way in which PfEMP1 functions and how it is neutralized by human antibodies are increasingly being uncovered on a structural level and are essential for understanding malaria pathology and ...

reduced mortality from experimental cerebral malaria in mice. The research, published in PNAS and funded by the Medical Research Council, also shows that animals treated with inflammasome inhibitors ...