Cerebral malaria (CM) is a complex of syndromes relating to the presence of Plasmodium falciparum-infected erythrocytes sequestering in the brain microvasculature. The mechanisms of pathology are ...

Following release from hepatocytes, each merozoite infects an erythrocyte, thus triggering the bloodstream stage of infection and the pathology that is associated with malaria. Earlier research ...

Such drugs will prevent pathology and interrupt transmission, and could therefore have an important role in the control of malaria and its eventual eradication. Given the increased commitment to ...

1 Vascular Immunology Unit, Department of Pathology, Sydney Medical School, The University of Sydney, Camperdown NSW 2042, Australia. Cerebral malaria (CM) is a complex of syndromes relating to ...

"The way in which PfEMP1 functions and how it is neutralized by human antibodies are increasingly being uncovered on a structural level and are essential for understanding malaria pathology and ...

A decade and a half later, he was back on campus—this time with malaria as his designated target. The disease persists as one of the developing world’s deadliest, in part because of the difficulty of ...

The way in which PfEMP1 functions and how it is neutralized by human antibodies are increasingly being uncovered on a structural level and are essential for understanding malaria pathology and ...

reduced mortality from experimental cerebral malaria in mice. The research, published in PNAS and funded by the Medical Research Council, also shows that animals treated with inflammasome inhibitors ...