The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the ...

Knowledge of a drug's mechanism of action enables better dosing through monitoring of the drug's effects on the target pathway in the patient. For example, the proper statin dosage for a given ...

Understanding the mechanisms of action of antithrombotic agents is also important for defining therapeutic strategies and managing adverse effects of these medications. The mechanisms by which the ...

BCL-2 inhibitors, such as venetoclax (Venclexta) work by targeting the BCL-2 protein, which plays a key role in preventing apoptosis, or programmed cell death. According to John Seymour, MD, ...

Such efforts have even been shown to lower humanitarian costs by as much as 30 percent, providing an average savings of US$2.8 for every US$1 invested. The Famine Action Mechanism (FAM) is a global ...